Preheat oven 350*
Beat first 3 ingredients at medium speed until well blended. Add egg and egg white one at a time, beating well after each addition. Lightly spoon flour into dry measuring cups: level with knife. Combine 2 tablespoons flour and blueberries in a small bowl, and toss well. Combine remaining flour, baking powder, soda, and salt. Add flour mixture to sugar mixture alternately with yogurt, beginning and ending with flour mixture. Fold in blueberry mixture and vanilla. Pour cake batter into 10-inch tube pan coated with cooking spray. Bake for one hour and ten minutes or until toothpick comes out clean.
Cool cake in pan 10 minutes; remove from pan.
Combine powdered sugar and lemon juice in a small bowl; drizzle over warm cake. Cut with serrated knife.